Description

4-(5-Chloro-2-Methylphenyl)Piperazinyl Morpholin-4-Yl Ketone is a high-purity synthetic organic compound belonging to the class of piperazine derivatives, valued for its role as a critical intermediate in advanced pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel therapeutic agents, particularly within the central nervous system (CNS) and other targeted drug discovery programs. Its specific molecular architecture makes it a key building block for synthesizing complex molecules with potential pharmacological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery.
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and optimizing new chemical entities in high-throughput screening and lead optimization studies.
• CNS Drug Development: Particularly relevant for research targeting neurological and psychiatric disorders due to its piperazine-morpholine pharmacophore.
• Process Chemistry & Scale-up: Employed in route scouting and process optimization for the commercial-scale manufacturing of candidate drugs.
• Biochemical Tool Compound: May be utilized in biochemical assays to study receptor-ligand interactions and enzyme inhibition.
• Contract Research & Manufacturing (CRO/CMO): Supplied to research organizations and manufacturers specializing in custom synthesis for the life sciences industry.

Basic Information

Product Name	4-(5-Chloro-2-Methylphenyl)Piperazinyl Morpholin-4-Yl Ketone
CAS No.	497060-50-1
Molecular Formula	C16H22ClN3O2
Molecular Weight	323.82 g/mol
Synonyms	1-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-2-morpholin-4-ylethanone; 4-(5-Chloro-o-tolyl)piperazin-1-yl morpholin-4-yl methanone; 4-(5-Chloro-2-methylphenyl)piperazin-1-yl(morpholino)methanone; N-Morpholino-4-(5-chloro-2-methylphenyl)piperazine-1-carboxamide; 497060-50-1; (Morpholin-4-yl)[4-(5-chloro-2-methylphenyl)piperazin-1-yl]methanone
EINECS	Contact for details

Quality Control

Our production of 4-(5-Chloro-2-Methylphenyl)Piperazinyl Morpholin-4-Yl Ketone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.