Description

(4-Hydroxypiperidin-1-Yl)Piperidin-3-Yl-Methanone is a high-purity, advanced pharmaceutical intermediate featuring a unique piperidine-based scaffold. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) therapeutics, kinase inhibitors, and other specialized medicinal compounds. Our supply ensures consistent quality and reliable availability for global R&D and production pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the research and process development stages for new Active Pharmaceutical Ingredients, particularly in oncology and CNS areas.
• Chemical Synthesis: Employed in organic synthesis for introducing the (4-hydroxypiperidin-1-yl)piperidin-3-yl-methanone moiety into more complex molecular architectures.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	(4-Hydroxypiperidin-1-Yl)Piperidin-3-Yl-Methanone
CAS No.	496057-57-9
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	1-(3-Piperidinylcarbonyl)-4-hydroxypiperidine; 4-Hydroxy-1-(3-piperidinylcarbonyl)piperidine; 3-[(4-Hydroxypiperidin-1-yl)carbonyl]piperidine; 1-(Piperidine-3-carbonyl)piperidin-4-ol; (4-Hydroxy-1-piperidinyl)(3-piperidinyl)methanone; 4-Hydroxy-N-(3-piperidinyl)-1-piperidinecarboxamide (tautomer)
EINECS	Contact for details

Quality Control

Our (4-Hydroxypiperidin-1-Yl)Piperidin-3-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.