Description

1-Piperazinepropanol,-Bta--Fluoro-4-Methyl-,(-Bta-S)-(9Ci) is a chiral, fluorinated piperazine derivative, a sophisticated organic building block of significant interest in advanced chemical synthesis. Its molecular architecture, featuring a piperazine core with a fluorinated methyl group and a propanol side chain, makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly those targeting the central nervous system and other specialized areas.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, especially in medicinal chemistry programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom and specific stereochemistry can enhance biological activity and stability.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and receptor interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	1-Piperazinepropanol,-Bta--Fluoro-4-Methyl-,(-Bta-S)-(9Ci)
CAS No.	492444-14-1
Molecular Formula	C8H17FN2O
Molecular Weight	176.24 g/mol
Synonyms	(S)-1-(3-Fluoro-4-methylphenyl)-3-(piperazin-1-yl)propan-1-ol; 1-Piperazinepropanol, β-fluoro-4-methyl-, (β-S)- (9CI); 492444-14-1; (S)-3-(Piperazin-1-yl)-1-(3-fluoro-4-methylphenyl)propan-1-ol; (β-S)-β-Fluoro-4-methyl-1-piperazinepropanol
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system aligned with ICH guidelines to ensure the integrity of our advanced intermediates. Every batch of 1-Piperazinepropanol,-Bta--Fluoro-4-Methyl-,(-Bta-S)-(9Ci) undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR, and MS for structural confirmation, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) documenting identity, purity (typically >97% by HPLC), and specific tests is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.