Description

Piperazine, 1-(Chloroacetyl)-4-(2-Pyridinyl)- (9Ci) is a specialized heterocyclic organic compound that serves as a crucial building block in advanced chemical synthesis. Its molecular architecture, featuring both piperazine and pyridine rings with a chloroacetyl functional group, makes it a versatile intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients. Its reliable quality and consistent supply are essential for accelerating innovation in drug discovery and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents, antimicrobials, and kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its structural motifs can contribute to specific modes of action.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Chelator Precursor: The nitrogen-rich structure makes it a potential starting material for synthesizing specialized ligands used in catalysis or metal complexation.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	Piperazine, 1-(Chloroacetyl)-4-(2-Pyridinyl)- (9Ci)
CAS No.	491837-81-1
Molecular Formula	C11H12ClN3O
Molecular Weight	237.69 g/mol
Synonyms	1-(Chloroacetyl)-4-(pyridin-2-yl)piperazine; 4-(2-Pyridinyl)-1-(chloroacetyl)piperazine; 2-[4-(Chloroacetyl)piperazin-1-yl]pyridine; N-(2-Pyridyl)-N'-(chloroacetyl)piperazine; 1-Chloroacetyl-4-(2-pyridyl)piperazine; 4-(Pyridin-2-yl)-1-(2-chloroacetyl)piperazine
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 1-(Chloroacetyl)-4-(2-Pyridinyl)- (9Ci) is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.