Description

Azd 2858 Hydrochloride is a high-purity, small molecule compound of significant interest in pharmaceutical research and development. This compound is valued for its role as a potent and selective inhibitor of specific kinase targets, making it a crucial tool for investigating cellular signaling pathways. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology, neurology, and metabolic disease research. Our supply ensures consistent quality and reliable availability for critical preclinical and development workflows.

Application

• Biochemical Research: Used as a selective kinase inhibitor to study signal transduction mechanisms in cell biology.
• Pharmaceutical R&D: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in drug discovery programs.
• Oncology Research: Investigated for its potential effects on cancer cell proliferation and survival pathways.
• Neurological Disease Models: Applied in research models for neurodegenerative diseases to understand kinase-related pathology.
• In Vitro & In Vivo Studies: Utilized in both cell-based assays and animal studies to evaluate pharmacokinetics and pharmacodynamics.
• High-Throughput Screening (HTS): Employed as a control compound in screening libraries to identify novel therapeutic agents.

Basic Information

Product Name	Azd 2858 Hydrochloride
CAS No.	486424-21-9
Molecular Formula	C₂₀H₂₀ClN₅O₂ • HCl
Molecular Weight	426.32 g/mol (free base: 389.86 g/mol)
Synonyms	AZD2858 Hydrochloride; AZD-2858 HCl; 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride; GSK-3 Inhibitor AZD2858; 1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-, hydrochloride (1:1); AZD 2858
EINECS	Contact for details

Quality Control

Every batch of Azd 2858 Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and residual solvents is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.