Description

1-Piperazineethanamine,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci) is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate stereochemically defined piperazine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the synthesis of advanced, stereospecific pesticides and herbicides.
• Chemical Biology: Serves as a scaffold for designing molecular probes and inhibitors to study biological pathways.
• Material Science: Potential precursor for chiral polymers or complexing agents with specific optical properties.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis projects requiring specific stereochemistry.

Basic Information

Product Name	1-Piperazineethanamine,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci)
CAS No.	486414-65-7
Molecular Formula	C8H19N3
Molecular Weight	157.26 g/mol
Synonyms	(3R,5S)-3,5-Dimethyl-1-(2-aminoethyl)piperazine; (3R,5S)-3,5-Dimethylpiperazin-1-ylethanamine; 2-[(3R,5S)-3,5-Dimethylpiperazin-1-yl]ethanamine; (3R,5S)-Rel-1-Piperazineethanamine, 3,5-Dimethyl-; (3R,5S)-3,5-Dimethyl-1-(2-aminoethyl)piperazine; 1-(2-Aminoethyl)-3,5-dimethylpiperazine, (3R,5S)-rel-; (rel)-(3R,5S)-3,5-Dimethyl-1-(2-aminoethyl)piperazine
EINECS	Contact for details

Quality Control

Our production of 1-Piperazineethanamine,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. We support compliance with cGMP, ICH guidelines, and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.