Description

1-Piperazinecarbonitrile,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci) is a high-purity, stereochemically defined piperazine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, nitrogen-containing scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific stereochemistry is required for biological activity. The product is supplied under stringent quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific isomer activity is targeted.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to induce stereoselectivity in chemical reactions.
• Chemical Research: Employed in academic and industrial R&D for methodological studies in heterocyclic and medicinal chemistry.
• Fine Chemical Production: Incorporated into the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1-Piperazinecarbonitrile,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci)
CAS No.	486414-64-6
Molecular Formula	C7H13N3
Molecular Weight	139.20 g/mol
Synonyms	(3R,5S)-3,5-Dimethylpiperazine-1-carbonitrile; rel-(3R,5S)-3,5-Dimethyl-1-piperazinecarbonitrile; 3,5-Dimethylpiperazine-1-carbonitrile (rel-(3R,5S)-isomer); (3R,5S)-3,5-Dimethylpiperazinecarbonitrile; 1-Cyano-3,5-dimethylpiperazine (stereoisomer); (rel-3R,5S)-3,5-Dimethyl-1-cyanopiperazine; 486414-64-6; (3R,5S)-rel-3,5-Dimethylpiperazine-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarbonitrile,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci) is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and synthesis. Each batch is characterized by techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.