Description

(S)-1,2-Dimethylpiperazine Dihydrochloride is a high-purity chiral piperazine derivative, supplied as a stable dihydrochloride salt. This compound is a critical chiral building block and ligand for asymmetric synthesis, offering precise stereochemical control in the development of active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where enantiomeric purity is paramount for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules, particularly in central nervous system (CNS) and antiviral therapeutics.
• Catalyst Ligand: Serves as a precursor for chiral ligands used in transition metal-catalyzed reactions, such as asymmetric hydrogenation and cross-coupling.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides to enhance target specificity and reduce environmental impact.
• Fine Chemical Synthesis: Employed in academic and industrial R&D for constructing complex molecular architectures with defined stereochemistry.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(S)-1,2-Dimethylpiperazine Dihydrochloride
CAS No.	485841-50-7
Molecular Formula	C6H16N2·2HCl
Molecular Weight	197.13 g/mol
Synonyms	(S)-1,2-Dimethylpiperazine Dihydrochloride; (S)-1,2-DMP·2HCl; (S)-1,2-Dimethylpiperazine Hydrochloride; (S)-1,2-Dimethylpiperazine Dihydrochloride Salt; (S)-1,2-Dimethylpiperazine 2HCl; (2S)-1,2-Dimethylpiperazine Dihydrochloride; (S)-(-)-1,2-Dimethylpiperazine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1,2-Dimethylpiperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.