Description

tert-Butyl 4-Cyclobutylpiperazine-1-Carboxylate is a high-purity, synthetically valuable piperazine derivative and a key protected intermediate in modern organic synthesis. Its core value lies in providing a versatile, nitrogen-rich scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Ligand and Catalyst Precursor: Used to develop specialized ligands for metal-catalyzed reactions or as a precursor for organocatalysts in asymmetric synthesis.
• Agrochemical Research: Employed in the discovery and development of new herbicides, fungicides, and insecticides that utilize the piperazine pharmacophore.
• Chemical Biology Probe Synthesis: Acts as a scaffold for creating molecular probes to study biological pathways and protein function.
• Polymer Modification: Can be incorporated into polymer backbones to impart specific chemical functionality or to modify material properties.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-Cyclobutylpiperazine-1-Carboxylate
CAS No.	485798-62-7
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	1-Boc-4-Cyclobutylpiperazine; 4-Cyclobutylpiperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyclobutyl-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-cyclobutylpiperazine; Boc-4-Cyclobutylpiperazine; N-Boc-4-Cyclobutylpiperazine; 485798-62-7; Cyclobutylpiperazine Boc-protected
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyclobutylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.