Description

Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3S,4S,6S)- is a high-purity, stereochemically defined bicyclic amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric catalysis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective synthesis.
• Agrochemical Research: Employed in the design and synthesis of new, stereospecific pesticides and herbicides.
• Peptidomimetics & Conformationally Restricted Peptides: Acts as a rigid, non-natural amino acid analog to induce specific secondary structures and enhance metabolic stability in peptide-based therapeutics.
• Material Science Research: Investigated as a monomer or cross-linker for creating polymers with unique thermal and mechanical properties.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up processes for complex organic molecule synthesis.

Basic Information

Product Name	Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3S,4S,6S)-
CAS No.	482377-73-1
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	(1R,2R,3S,4S,6S)-3-Aminobicyclo[2.2.1]heptane-2,5-dicarboxylic acid; (1R,2R,3S,4S,6S)-3-Amino-2,5-norbornanedicarboxylic acid; endo-3-Aminobicyclo[2.2.1]heptane-2-endo,5-endo-dicarboxylic acid; 3-Amino-2,5-norbornanedicarboxylic acid (specific stereoisomer); Chiral NBDA derivative; Bicyclic β-amino acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, chiral analysis, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.