Description

(2-(1-Piperidinylmethyl)Phenyl)Magnesium Chloride is a highly reactive organomagnesium reagent, specifically an aryl Grignard reagent. This compound is a critical building block in advanced organic synthesis, enabling the formation of new carbon-carbon bonds with high precision and efficiency. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the (2-(1-piperidinylmethyl)phenyl) moiety into target molecules during the development of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides that require specific aryl group functionalization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for conductive polymers.
• Cross-Coupling Reactions: Acts as a nucleophilic coupling partner in palladium-catalyzed reactions (e.g., Kumada coupling) to form biaryl structures.
• Nucleophilic Addition to Carbonyls: Used for the addition to aldehydes, ketones, and esters to produce secondary and tertiary alcohols.

Basic Information

Item	Detail
Product Name	(2-(1-Piperidinylmethyl)Phenyl)Magnesium Chloride
CAS No.	480424-81-5
Molecular Formula	C12H16ClMgN
Molecular Weight	233.99 g/mol
Synonyms	2-(Piperidin-1-ylmethyl)phenylmagnesium chloride; (2-(Piperidin-1-ylmethyl)phenyl)magnesium chloride; 1-[2-(Chloromagnesio)benzyl]piperidine; Grignard Reagent from 1-(2-Bromobenzyl)piperidine; (2-Piperidin-1-ylmethyl-phenyl)-magnesium chloride
EINECS	Contact for details

Quality Control

Every batch of our (2-(1-Piperidinylmethyl)Phenyl)Magnesium Chloride is manufactured and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, concentration, and solvent content, ensuring traceability and consistency for your critical synthetic applications. Our quality systems are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Store away from heat, sparks, and open flame in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Solution (typically in THF or Diethyl Ether)
Concentration	0.5 M - 2.0 M in solvent
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.