Description

2-Chloro-6-((3-Chlorobenzyl)Oxy)Pyrazine is a high-purity, functionalized pyrazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine core.
• Ligand and Catalyst Development: Used in organometallic chemistry for the preparation of specialized ligands that modulate catalytic activity in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring precise functionalization on the pyrazine ring.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study biological processes and enzyme functions.

Basic Information

Product Name	2-Chloro-6-((3-Chlorobenzyl)Oxy)Pyrazine
CAS No.	479685-04-6
Molecular Formula	C11H8Cl2N2O
Molecular Weight	255.10 g/mol
Synonyms	2-Chloro-6-[(3-chlorophenyl)methoxy]pyrazine; 6-Chloro-3-((3-chlorobenzyl)oxy)pyrazine; Pyrazine, 2-chloro-6-[(3-chlorophenyl)methoxy]-; 2-Chloro-6-(3-chlorobenzyloxy)pyrazine; 479685-04-6; 2-Chloro-6-(3-chlorobenzyloxy)pyrazine; 2-Chloro-6-[(3-chlorobenzyl)oxy]pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-((3-Chlorobenzyl)Oxy)Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.