Description

1-Boc-β-Oxo-4-Piperidinepropanoic Acid Methyl Ester is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within the central nervous system (CNS) and metabolic disorder therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-containing drug candidates and bioactive molecules.
• Medicinal Chemistry Research: Used in scaffold hopping and structure-activity relationship (SAR) studies to optimize lead compounds.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and optimization of API manufacturing routes.
• Protease Inhibitor Development: Potential building block for inhibitors targeting various protease enzymes.
• Chemical Biology: Can be utilized in the synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: A versatile substrate for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical services.

Basic Information

Product Name	1-Boc-β-Oxo-4-Piperidinepropanoic Acid Methyl Ester
CAS No.	479630-02-9
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	1-Boc-3-oxo-4-piperidinepropanoic acid methyl ester; Methyl 3-(1-((tert-butoxy)carbonyl)-3-oxopiperidin-4-yl)propanoate; 4-Piperidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-3-oxo-, methyl ester; tert-Butyl 4-(2-methoxy-2-oxoethyl)-3-oxopiperidine-1-carboxylate; 1-Boc-4-(2-methoxy-2-oxoethyl)-3-oxopiperidine; 1-Boc-3-oxo-piperidine-4-propionic acid methyl ester; 1-Boc-4-(2-methoxy-2-oxoethyl)-3-oxo-piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-β-Oxo-4-Piperidinepropanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.