Description

Amino-Peg11-Amine is a high-purity, bifunctional polyethylene glycol (PEG) derivative featuring a primary amine group at each terminus of an 11-unit PEG spacer. This molecular architecture is critical for creating flexible, hydrophilic linkers in bioconjugation and materials science. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, soluble spacers for coupling reactions, surface modification, and the synthesis of complex macromolecular structures.

Application

• Bioconjugation and Cross-linking: Serves as a versatile heterobifunctional linker for attaching proteins, peptides, antibodies, or other biomolecules to surfaces, nanoparticles, or other polymers, introducing solubility and a long, flexible tether.
• PEGylation Reagent: Used in the development of PEGylated therapeutic proteins and peptides to enhance solubility, prolong circulation half-life, and reduce immunogenicity.
• Dendrimer and Polymer Synthesis: Acts as a core or branching unit in the construction of dendrimers, star polymers, and hydrogels due to its dual-reactive amine groups.
• Surface Functionalization: Employed to create amine-terminated self-assembled monolayers (SAMs) on gold, silicon, or other substrates for subsequent immobilization of biomolecules or catalysts.
• Nanoparticle Coating: Provides a stable, hydrophilic, and functionalizable coating on quantum dots, liposomes, and metallic nanoparticles to improve biocompatibility and enable targeted delivery.
• Diagnostic Reagent Intermediate: Used in the synthesis of contrast agents, fluorescent probes, and other diagnostic tools where a hydrophilic spacer is required between a targeting moiety and a signaling molecule.

Basic Information

Product Name	Amino-Peg11-Amine
CAS No.	479200-82-3
Molecular Formula	C24H50N2O11
Molecular Weight	542.7 g/mol
Synonyms	α,ω-Bis(2-aminoethoxy)undeca(ethylene glycol); 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatetracontane-1,45-diamine; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethanamine) PEG derivative; H2N-PEG11-NH2; Bis-amino PEG 11; Amino-PEG11-Amino; NH2-PEG11-NH2; PEG 550 diamine
EINECS	Contact for details

Quality Control

Our Amino-Peg11-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H and ¹³C) and HPLC for identity and purity verification, and titration for amine value determination. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring it meets the stringent requirements for research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and potentially oxidizable nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.