Description

(S)-3-n-Cbz-Amino-Piperidine CAS NO 478646-33-2 is a high-purity, chiral piperidine derivative featuring a carboxybenzyl (Cbz) protecting group on the amino functionality. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex, biologically active molecules with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring precise stereocontrol such as neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and commercial synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetics Development: Serves as a constrained, chiral scaffold in the design of peptide analogs and mimetics.
• Catalyst and Ligand Synthesis: A precursor for the preparation of chiral catalysts and ligands used in homogeneous catalysis.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(S)-3-n-Cbz-Amino-Piperidine
CAS No.	478646-33-2
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	(S)-1-[(Benzyloxy)carbonyl]-3-aminopiperidine; (S)-3-(N-Cbz-Amino)piperidine; (S)-N-Cbz-3-Aminopiperidine; (S)-3-Amino-1-(benzyloxycarbonyl)piperidine; (S)-1-Cbz-3-aminopiperidine; (3S)-1-[(Phenylmethoxy)carbonyl]-3-piperidinamine; (S)-3-(Benzyloxycarbonylamino)piperidine
EINECS	Contact for details

Quality Control

Our (S)-3-n-Cbz-Amino-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.