Description

Tri-o-Acetyl-D-[6-13C]Glucal is a stable isotope-labeled derivative of glucal, specifically enriched with carbon-13 at the 6-position. This compound is a critical intermediate in the synthesis of isotopically labeled carbohydrates, glycoconjugates, and nucleosides for advanced research and development. It is essential for scientists in pharmaceutical research, metabolic studies, and analytical chemistry who require precise molecular tracers. The product is supplied with a high level of isotopic and chemical purity to ensure reliable and reproducible experimental results.

Application

• Pharmaceutical Research & Development: As a key building block for the synthesis of carbon-13 labeled active pharmaceutical ingredients (APIs), prodrugs, and diagnostic agents.
• Metabolic Pathway Tracing: Used in isotope labeling studies to elucidate biochemical pathways, enzyme mechanisms, and drug metabolism (pharmacokinetics) in vivo and in vitro.
• Glycobiology & Glycochemistry: Serves as a precursor for the preparation of isotopically labeled complex carbohydrates, oligosaccharides, and glycoconjugates for structural and functional studies.
• NMR Spectroscopy & Mass Spectrometry: Provides an internal standard or a probe molecule in analytical method development for quantitative analysis and structural elucidation.
• Chemical Biology Probes: Enables the creation of tagged molecules for investigating protein-carbohydrate interactions and cellular processes.
• Academic & Institutional Research: A vital reagent for synthetic organic chemists and biochemists working on isotope-incorporated natural products and novel synthetic methodologies.

Basic Information

Item	Details
Product Name	Tri-o-Acetyl-D-[6-13C]Glucal
CAS No.	478529-37-2
Molecular Formula	C12H1613CO8 *
Molecular Weight	289.25 g/mol (for 13C1 isotopologue)
Synonyms	1,5-Anhydro-2-deoxy-D-arabino-hex-1-enitol 3,4,6-Triacetate-6-13C; (3R,4R,5R)-4-Acetoxy-5-(acetoxymethyl)-3-[(acetyloxy)-13C]methyl]-3,4-dihydro-2H-pyran; D-Glucal Triacetate-6-13C; Tri-O-acetyl-1,5-anhydro-2-deoxy-D-arabino-hex-1-enitol-6-13C; 6-13C-Labeled Tri-O-acetyl-D-glucal; Isotopically Labeled Glucal Triacetate
EINECS	Contact for details

* Formula indicates 13C enrichment at the specified position.

Quality Control

Every batch of Tri-o-Acetyl-D-[6-13C]Glucal is manufactured and analyzed under strict quality protocols to ensure high isotopic and chemical purity. Our quality system is designed to meet the exacting requirements of research and development. Certificates of Analysis (COA) are provided, detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity by HPLC, and identity confirmation by NMR and MS. We support compliance with various research standards and can provide documentation to meet specific institutional or regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99% at position 6
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.