Description

2-Amino-2-Deoxy-D-[1-13C]Galactose Hydrochloride is a stable isotope-labeled derivative of galactosamine, a fundamental building block in glycobiology and biochemistry. This compound is essential for advanced research and development, providing a critical tool for metabolic pathway tracing, structural elucidation, and quantitative analysis using techniques like NMR and mass spectrometry. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers working on carbohydrate-based therapeutics, biomarker discovery, and complex biochemical assays.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer to study the biosynthesis and catabolism of glycosaminoglycans (GAGs) like chondroitin sulfate and keratan sulfate in cell culture and in vivo models.
• Biomarker Research & Diagnostics: Serves as an internal standard for the accurate quantification of galactosamine and related metabolites in biological fluids (e.g., plasma, urine) via LC-MS/MS, aiding in the study of metabolic disorders.
• Glycoprotein & Glycolipid Analysis: Employed in the structural analysis and metabolic labeling of glycoconjugates to understand their function in cell signaling, immune response, and disease mechanisms.
• Pharmaceutical Development: Integral in the research phase for developing carbohydrate-based drugs, vaccines, and enzyme replacement therapies, where precise tracking of drug metabolism is required.
• NMR Spectroscopy Studies: Provides a 13C-enriched probe for nuclear magnetic resonance (NMR) studies, enabling detailed investigation of molecular structure, dynamics, and interactions in solution.
• Enzymology & Biochemical Assays: Acts as a substrate or inhibitor for enzymes like galactokinase or galactosamine-6-sulfatase in kinetic studies and high-throughput screening assays.

Basic Information

Product Name	2-Amino-2-Deoxy-D-[1-13C]Galactose Hydrochloride
CAS No.	478518-54-6
Molecular Formula	C513CH12NO5•HCl
Molecular Weight	217.61 g/mol
Synonyms	D-[1-13C]Galactosamine Hydrochloride; 2-Amino-2-deoxy-D-[1-13C]galactopyranose Hydrochloride; [1-13C]-GalN HCl; Isotopically Labeled Galactosamine HCl; 2-Amino-2-deoxy-D-galactose-1-13C Hydrochloride; Chondrosamine-1-13C Hydrochloride; (2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal-1-13C Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Deoxy-D-[1-13C]Galactose Hydrochloride is manufactured under controlled conditions to ensure the highest isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to stringent in-house quality standards to ensure batch-to-batch consistency and reliability for sensitive analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.