Description

1,1,1-Trifluoro-3-[4-(4-Nitrophenyl)Piperazino]-2-Propanol is a high-value, fluorinated piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides and pesticides, where the trifluoromethyl and piperazine groups can impart improved efficacy and environmental profile.
• Fluorinated Compound Research: Serves as a valuable precursor in academic and industrial research focused on introducing fluorine atoms into complex molecular architectures to modulate lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Potential use in designing novel ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs) in material science applications.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	1,1,1-Trifluoro-3-[4-(4-Nitrophenyl)Piperazino]-2-Propanol
CAS No.	478258-73-0
Molecular Formula	C13H15F3N3O3
Molecular Weight	318.27 g/mol
Synonyms	1,1,1-Trifluoro-3-(4-(4-nitrophenyl)piperazin-1-yl)propan-2-ol; 2-Propanol, 1,1,1-trifluoro-3-[4-(4-nitrophenyl)-1-piperazinyl]-; 3-[4-(4-Nitrophenyl)piperazin-1-yl]-1,1,1-trifluoropropan-2-ol; 1,1,1-Trifluoro-3-(4-(4-nitrophenyl)piperazin-1-yl)-2-propanol; 1-(4-Nitrophenyl)-4-(2-hydroxy-3,3,3-trifluoropropyl)piperazine; 478258-73-0
EINECS	Contact for details

Quality Control

Our production of 1,1,1-Trifluoro-3-[4-(4-Nitrophenyl)Piperazino]-2-Propanol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality system is designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.