Description

Ethyl 3-[4-(4-Fluorophenyl)Piperazino]-2-(Methoxyimino)Propanoate is a high-purity synthetic intermediate of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new chemical entities and optimizing synthetic routes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides requiring specific fluorinated piperazine motifs.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme inhibition and receptor binding.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the commercial manufacturing of APIs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Ethyl 3-[4-(4-Fluorophenyl)Piperazino]-2-(Methoxyimino)Propanoate
CAS No.	478077-51-9
Molecular Formula	C16H22FN3O3
Molecular Weight	323.37 g/mol
Synonyms	Ethyl 2-(Methoxyimino)-3-[4-(4-fluorophenyl)piperazin-1-yl]propanoate; 1-(4-Fluorophenyl)-4-[(1-methoxyimino-2-ethoxy-2-oxoethyl)]piperazine; 478077-51-9; Ethyl 3-(4-(4-fluorophenyl)piperazin-1-yl)-2-(methoxyimino)propanoate; Propanoic acid, 3-[4-(4-fluorophenyl)-1-piperazinyl]-2-[(methoxyimino)]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-[4-(4-Fluorophenyl)Piperazino]-2-(Methoxyimino)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.