Description

1-[(4-Methoxyphenyl)Sulfonyl]-4-[3-(Trifluoromethyl)-2-Pyridinyl]Piperazine is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules for preclinical and clinical studies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CMOs for the scale-up and cGMP production of investigational new drugs (INDs).
• Biochemical Research: Potential use as a reference standard or a tool compound in pharmacological assays and target validation.

Basic Information

Product Name	1-[(4-Methoxyphenyl)Sulfonyl]-4-[3-(Trifluoromethyl)-2-Pyridinyl]Piperazine
CAS No.	478077-41-7
Molecular Formula	C17H18F3N3O3S
Molecular Weight	401.40 g/mol
Synonyms	4-[3-(Trifluoromethyl)pyridin-2-yl]-1-[(4-methoxyphenyl)sulfonyl]piperazine; 1-(4-Methoxybenzenesulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine; 4-(3-Trifluoromethyl-2-pyridinyl)-1-(4-methoxyphenylsulfonyl)piperazine; CAS 478077-41-7
EINECS	Contact for details

Quality Control

Our 1-[(4-Methoxhenyl)Sulfonyl]-4-[3-(Trifluoromethyl)-2-Pyridinyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.