Description

3-(4-Benzyl-Piperazin-1-Yl)-1,1,1-Trifluoro-Propan-2-Ol is a specialized trifluoromethylated piperazine derivative, a high-value building block in advanced organic synthesis. Its molecular structure, featuring both a piperazine ring and a trifluoromethyl alcohol group, makes it a critical intermediate for developing novel bioactive compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorine and specific nitrogen-containing pharmacophores into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antimicrobial agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on the synthesis and properties of organofluorine molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of tailored compounds for client-specific projects.

Basic Information

Product Name	3-(4-Benzyl-Piperazin-1-Yl)-1,1,1-Trifluoro-Propan-2-Ol
CAS No.	478050-24-7
Molecular Formula	C14H19F3N2O
Molecular Weight	288.31 g/mol
Synonyms	1,1,1-Trifluoro-3-(4-benzylpiperazin-1-yl)propan-2-ol; 3-(4-Benzyl-1-piperazinyl)-1,1,1-trifluoro-2-propanol; 1,1,1-Trifluoro-3-(4-benzyl-1-piperazinyl)-2-propanol; 2-Propanol, 1,1,1-trifluoro-3-(4-benzyl-1-piperazinyl)-; 3-(4-Benzylpiperazin-1-yl)-1,1,1-trifluoropropan-2-ol; 478050-24-7; BPP-TFP
EINECS	Contact for details

Quality Control

Our 3-(4-Benzyl-Piperazin-1-Yl)-1,1,1-Trifluoro-Propan-2-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.