Description

4-(4-[(4-Methoxyphenyl)Sulfonyl]Piperazino)Benzenecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperazine and benzenecarbonitrile structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and receptor-specific therapies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale reactions to construct complex molecules for medicinal chemistry programs.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Life Science Research: Utilized in biochemical and pharmacological studies to investigate structure-activity relationships (SAR).
• Process Chemistry Development: Applied in route scouting and optimization for the scalable production of target APIs.

Basic Information

Product Name	4-(4-[(4-Methoxyphenyl)Sulfonyl]Piperazino)Benzenecarbonitrile
CAS No.	478046-93-4
Molecular Formula	C18H19N3O3S
Molecular Weight	357.43 g/mol
Synonyms	4-[4-(4-Methoxyphenyl)sulfonylpiperazin-1-yl]benzonitrile; 1-(4-Cyanophenyl)-4-(4-methoxyphenyl)sulfonylpiperazine; 4-(4-(4-Methoxyphenylsulfonyl)piperazin-1-yl)benzonitrile; Benzonitrile, 4-[4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl]-; 4-(4-(4-Methoxyphenylsulfonyl)piperazino)benzonitrile; 478046-93-4; 4-(4-(4-Methoxybenzenesulfonyl)piperazin-1-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(4-[(4-Methoxyphenyl)Sulfonyl]Piperazino)Benzenecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.