Description

2-[4-(4-Fluorophenyl)Piperazino]-1-(2-Thienyl)-1-Ethanone is a high-purity synthetic organic compound featuring a distinct piperazine-thiophene core structure, making it a valuable intermediate for advanced pharmaceutical and agrochemical research. This compound is critical for medicinal chemistry programs focused on developing novel therapeutic agents, particularly within the central nervous system (CNS) and metabolic disorder spaces. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for use in lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead molecules.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Potential precursor in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-[4-(4-Fluorophenyl)Piperazino]-1-(2-Thienyl)-1-Ethanone
CAS No.	478043-79-7
Molecular Formula	C16H17FN2OS
Molecular Weight	304.38 g/mol
Synonyms	1-(2-Thienyl)-2-[4-(4-fluorophenyl)-1-piperazinyl]ethanone; 2-[4-(4-Fluorophenyl)-1-piperazinyl]-1-(2-thienyl)ethanone; 4-(4-Fluorophenyl)-1-[2-(2-thienyl)-2-oxoethyl]piperazine; 2-(4-(4-Fluorophenyl)piperazin-1-yl)-1-(thiophen-2-yl)ethan-1-one; 478043-79-7; Ethanone, 1-(2-thienyl)-2-[4-(4-fluorophenyl)-1-piperazinyl]-
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Fluorophenyl)Piperazino]-1-(2-Thienyl)-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.