Description

1-[4-(3-Fluoropropoxy)Benzyl]-4-Phenylpiperazine is a high-purity, synthetic organic compound belonging to the phenylpiperazine class. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for CNS-targeting therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Utilized in pharmacological studies to investigate interactions with serotonin and dopamine receptor systems.
• Custom Synthesis: Starting material for the preparation of more complex, fluorinated derivatives with tailored biological activity.

Basic Information

Item	Details
Product Name	1-[4-(3-Fluoropropoxy)Benzyl]-4-Phenylpiperazine
CAS No.	477870-97-6
Molecular Formula	C20H25FN2O
Molecular Weight	328.43 g/mol
Synonyms	1-[[4-(3-Fluoropropoxy)phenyl]methyl]-4-phenylpiperazine; 4-Phenyl-1-[[4-(3-fluoropropoxy)phenyl]methyl]piperazine; 1-(4-(3-Fluoropropoxy)benzyl)-4-phenylpiperazine; N-[(4-(3-Fluoropropoxy)phenyl)methyl]-N'-phenylpiperazine; 477870-97-6; 1-[4-(3-Fluoropropoxy)benzyl]-4-phenyl-piperazine; 4-Phenyl-1-[4-(3-fluoropropoxy)benzyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-[4-(3-Fluoropropoxy)Benzyl]-4-Phenylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.