Description

2-(4-Methoxyphenyl)-2-[3-(Trifluoromethyl)-2-Quinoxalinyl]Acetonitrile is a high-value, specialized organic intermediate featuring a quinoxaline core and a trifluoromethyl group, which imparts unique electronic and steric properties. This compound is critical for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Acts as a precursor for the synthesis of organic electronic materials, such as ligands for OLEDs or charge-transport materials, due to its conjugated quinoxaline system.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(4-Methoxyphenyl)-2-[3-(Trifluoromethyl)-2-Quinoxalinyl]Acetonitrile
CAS No.	477867-64-4
Molecular Formula	C₁₈H₁₂F₃N₃O
Molecular Weight	343.30 g/mol
Synonyms	2-(4-Methoxyphenyl)-2-(3-(trifluoromethyl)quinoxalin-2-yl)acetonitrile; 2-(4-Methoxyphenyl)-2-(3-trifluoromethyl-2-quinoxalinyl)acetonitrile; 2-(3-(Trifluoromethyl)quinoxalin-2-yl)-2-(4-methoxyphenyl)acetonitrile; (4-Methoxyphenyl)(3-(trifluoromethyl)quinoxalin-2-yl)acetonitrile; CAS 477867-64-4; Quinoxaline-2-acetonitrile, 3-(trifluoromethyl)-α-(4-methoxyphenyl)-; α-(4-Methoxyphenyl)-3-(trifluoromethyl)-2-quinoxalineacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxyphenyl)-2-[3-(Trifluoromethyl)-2-Quinoxalinyl]Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.