Description

1-[(2-Methoxy-1-Naphthyl)Sulfinyl]-4-[3-(Trifluoromethyl)Phenyl]Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfinyl-piperazine structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential antipsychotic and neuroleptic drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• High-Throughput Screening (HTS): Serves as a core scaffold for generating compound libraries to identify new bioactive molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes for preclinical and clinical trial material production.
• Reference Standard: Used as an analytical standard for quality control and method validation in API manufacturing.
• Academic Research: Facilitates studies in organic synthesis and the development of new catalytic methodologies for sulfoxide formation.

Basic Information

Product Name	1-[(2-Methoxy-1-Naphthyl)Sulfinyl]-4-[3-(Trifluoromethyl)Phenyl]Piperazine
CAS No.	477762-11-1
Molecular Formula	C22H21F3N2O2S
Molecular Weight	434.48 g/mol
Synonyms	4-[3-(Trifluoromethyl)phenyl]-1-[(2-methoxynaphthalen-1-yl)sulfinyl]piperazine; 1-[(2-Methoxy-1-naphthyl)sulfinyl]-4-[3-(trifluoromethyl)phenyl]piperazine; 1-(2-Methoxy-1-naphthylsulfinyl)-4-(3-trifluoromethylphenyl)piperazine; 1-(2-Methoxynaphthalen-1-ylsulfinyl)-4-[3-(trifluoromethyl)phenyl]piperazine; 477762-11-1; 1-(2-Methoxy-1-naphthylsulfinyl)-4-(3-trifluoromethylphenyl)piperazine; 1-(2-Methoxynaphthalen-1-ylsulfinyl)-4-(3-trifluoromethylphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[(2-Methoxy-1-Naphthyl)Sulfinyl]-4-[3-(Trifluoromethyl)Phenyl]Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.