Description

1-(4-Chlorophenyl)-3-[4-(4-Nitrophenyl)Piperazino]-1-Propanone is a high-purity, synthetic organic compound belonging to the piperazine derivative class, serving as a crucial advanced pharmaceutical intermediate. Its molecular structure, featuring both chlorophenyl and nitrophenyl moieties, makes it a valuable building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for CNS-targeting therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Serves as a precursor for more complex molecules in custom synthesis and contract manufacturing.
• Biochemical Research: Potential tool compound for investigating biological pathways involving specific receptor interactions.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development.

Basic Information

Product Name	1-(4-Chlorophenyl)-3-[4-(4-Nitrophenyl)Piperazino]-1-Propanone
CAS No.	477328-84-0
Molecular Formula	C19H20ClN3O3
Molecular Weight	373.84 g/mol
Synonyms	1-(4-Chlorophenyl)-3-[4-(4-nitrophenyl)-1-piperazinyl]-1-propanone; 3-[4-(4-Nitrophenyl)piperazin-1-yl]-1-(4-chlorophenyl)propan-1-one; 1-Propanone, 1-(4-chlorophenyl)-3-[4-(4-nitrophenyl)-1-piperazinyl]-; 477328-84-0; 4-Chlorophenyl 3-[4-(4-nitrophenyl)piperazino]propyl ketone; (4-Chlorophenyl){3-[4-(4-nitrophenyl)piperazin-1-yl]propyl}methanone
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-3-[4-(4-Nitrophenyl)Piperazino]-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.