Description

3,4-Piperidinediol,6-(Hydroxymethyl)-,(3R,4S,6S)-Rel-(9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its multifunctional structure, which provides multiple points for chemical modification, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Chemical Research: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to create novel chiral ligands for asymmetric synthesis, enhancing enantioselectivity in catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and specialty materials requiring high stereochemical purity.

Basic Information

Product Name	3,4-Piperidinediol,6-(Hydroxymethyl)-,(3R,4S,6S)-Rel-(9Ci)
CAS No.	477253-23-9
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(3R,4S,6S)-6-(Hydroxymethyl)piperidine-3,4-diol; rel-(3R,4S,6S)-6-(Hydroxymethyl)-3,4-piperidinediol; (3R,4S,6S)-6-(Hydroxymethyl)-3,4-dihydroxypiperidine; 6-(Hydroxymethyl)-3,4-piperidinediol (stereoisomer); CAS 477253-23-9; Piperidine-3,4-diol, 6-(hydroxymethyl)-, (3R,4S,6S)-rel-
EINECS	Contact for details

Quality Control

Our 3,4-Piperidinediol,6-(Hydroxymethyl)-,(3R,4S,6S)-Rel-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.