Description

(1-Benzylpiperazin-2-Yl)Methanol is a versatile piperazine derivative building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. Pharmaceutical research and development laboratories need it for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in neurological and therapeutic agent discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the research and development of novel drug candidates, particularly for central nervous system (CNS) targets.
• Organic Synthesis Building Block: Used in the construction of complex piperazine-containing molecules for medicinal chemistry and agrochemical research.
• Ligand Synthesis: Employed in the development of chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Chemical Reference Standard: Utilized as a high-purity standard in analytical method development and quality control for related compounds.
• Academic & Industrial R&D: A valuable reagent for investigating structure-activity relationships (SAR) in life sciences and material science research.

Basic Information

Product Name	(1-Benzylpiperazin-2-Yl)Methanol
CAS No.	476493-27-3
Molecular Formula	C12H18N2O
Molecular Weight	206.29 g/mol
Synonyms	1-Benzyl-2-(hydroxymethyl)piperazine; (1-Benzylpiperazin-2-yl)methanol; 2-(Hydroxymethyl)-1-benzylpiperazine; 1-Benzyl-2-piperazinemethanol; Benzylpiperazinylmethanol; (1-Benzyl-2-piperazinyl)methanol; α-(Hydroxymethyl)-N-benzylpiperazine
EINECS	Contact for details

Quality Control

Our (1-Benzylpiperazin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.