Description

2-Piperazinemethanol,1-Methyl-,(2S)-(9Ci) is a chiral piperazine derivative, a high-value building block in advanced organic synthesis. Its stereochemical purity and functionalized structure make it a critical intermediate for developing enantiomerically pure pharmaceuticals. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing compound libraries in drug discovery programs targeting various receptors.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for complex molecules requiring high enantiomeric excess.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, agrochemicals, and other performance materials where chirality is essential.

Basic Information

Product Name	2-Piperazinemethanol,1-Methyl-,(2S)-(9Ci)
CAS No.	476493-08-0
Molecular Formula	C6H14N2O
Molecular Weight	130.19 g/mol
Synonyms	(2S)-1-Methyl-2-piperazinemethanol; (S)-1-Methyl-2-piperazinemethanol; 1-Methyl-2-piperazinemethanol, (S)-; (S)-1-Methylpiperazine-2-methanol; 1-Methylpiperazine-2-methanol, (S)-; (S)-2-(Hydroxymethyl)-1-methylpiperazine; 476493-08-0; (2S)-1-Methylpiperazine-2-methanol
EINECS	Contact for details

Quality Control

We supply 2-Piperazinemethanol,1-Methyl-,(2S)-(9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are available upon request. We can support development projects with material meeting custom specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.