Description

2-Piperidinone, 4-Hydroxy-6-Methoxy-, (4R,6R)-Rel- (9Ci) is a high-purity chiral piperidinone derivative, a critical advanced pharmaceutical intermediate (API) and building block in organic synthesis. Its precise stereochemistry and functional groups make it invaluable for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to produce single-enantiomer compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value organic compounds requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	2-Piperidinone, 4-Hydroxy-6-Methoxy-, (4R,6R)-Rel- (9Ci)
CAS No.	476014-80-9
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(4R,6R)-4-Hydroxy-6-methoxy-2-piperidinone; (4R,6R)-4-Hydroxy-6-methoxypiperidin-2-one; rel-(4R,6R)-4-Hydroxy-6-methoxy-2-piperidinone; 4-Hydroxy-6-methoxy-2-piperidinone, (4R,6R)-rel-; (4R,6R)-rel-4-Hydroxy-6-methoxy-2-piperidinone; 2-Piperidinone, 4-hydroxy-6-methoxy-, (4R,6R)-rel-; Chiral 4-Hydroxy-6-methoxypiperidin-2-one
EINECS	Contact for details

Quality Control

Our 2-Piperidinone, 4-Hydroxy-6-Methoxy-, (4R,6R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR, and IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.