Description

n-Stearoyl 4-Hydroxysphinganine (Saccharomyces Cerevisiae) is a specific, high-purity sphingolipid derivative, a key intermediate in the study of complex lipid metabolism and signaling pathways. Its value lies in providing researchers and developers with a well-defined molecular tool for investigating ceramide biosynthesis, cellular stress responses, and membrane biology. This compound is essential for biochemical research, pharmaceutical development, and the production of reference standards in analytical laboratories.

Application

• Biochemical Research: Used as a critical substrate or intermediate in enzymatic studies related to sphingolipid metabolism, particularly for investigating ceramide synthases and related pathways.
• Pharmaceutical R&D: Serves as a building block or reference compound in the development of novel therapeutics targeting lipid-related disorders, cancer, and metabolic diseases.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for the qualitative and quantitative analysis of sphingolipids via LC-MS, HPLC, and other chromatographic techniques.
• Cell Biology Studies: Applied in cell culture experiments to study the effects of specific sphingolipid species on cell proliferation, apoptosis, and signal transduction mechanisms.
• Cosmeceutical Research: Investigated for its potential role in skin barrier function and as a precursor for bioactive lipids in advanced skincare formulations.
• Enzyme Characterization: Utilized as a defined substrate for the assay and kinetic characterization of enzymes involved in sphingolipid biosynthesis and degradation.

Basic Information

Product Name	n-Stearoyl 4-Hydroxysphinganine (Saccharomyces Cerevisiae)
CAS No.	475995-75-6
Molecular Formula	C36H73NO4
Molecular Weight	583.98 g/mol
Synonyms	N-Stearoylphytosphingosine; (2S,3S,4R)-2-[(1-Hydroxyoctadecylidene)amino]-1,3,4-octadecanetriol; C18-Phytosphingosine N-stearoylamide; Phytosphingosine N-stearate; N-Octadecanoylphytosphingosine; D-erythro-N-Stearoylphytosphingosine; Ceramide (d18:0/18:0) precursor
EINECS	Contact for details

Quality Control

Every batch of n-Stearoyl 4-Hydroxysphinganine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by NMR/MS), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed container under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and ensure stability. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.