Description

L-α-Lysophosphatidylethanolamine Plasmalogen (Brain, Porcine) is a specialized, high-purity phospholipid derivative isolated from porcine brain tissue, characterized by its unique vinyl ether bond at the sn-1 position. This compound is a critical bioactive lipid mediator and structural component, essential for research into cellular membrane dynamics, signaling, and neurological health. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on lipidomics, neurodegenerative disease models, and the development of advanced lipid-based delivery systems.

Application

• Biomedical Research Standard: Used as a critical reference standard in mass spectrometry-based lipidomic profiling and analytical method development.
• Neurological Disease Studies: Essential for in vitro and in vivo research on Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions linked to plasmalogen deficiency.
• Cell Membrane & Signaling Research: Investigated for its role in membrane fluidity, raft formation, and as a precursor for lipid second messengers.
• Pharmaceutical Development: Serves as a key intermediate or active component in the formulation of novel neuroprotective therapeutics and advanced drug delivery vehicles like liposomes.
• Diagnostic Reagent Manufacturing: Incorporated into assay kits and calibrators for the clinical measurement of plasmalogen levels.
• Biochemical & Enzymology Studies: Employed as a specific substrate for studying the activity of phospholipases and other lipid-metabolizing enzymes.

Basic Information

Product Name	L-α-Lysophosphatidylethanolamine Plasmalogen (Brain, Porcine)
CAS No.	475995-55-2
Molecular Formula	C23H46NO7P (Representative for C16:0)
Molecular Weight	479.58 g/mol (Representative for C16:0)
Synonyms	1-(1Z-Alkenyl)-sn-glycero-3-phosphoethanolamine; Lysoplasmenylethanolamine; Plasmalogen Lysophosphatidylethanolamine; 1-O-(1Z-Alkenyl)-2-hydroxy-sn-glycero-3-phosphoethanolamine; LPE-Plasmalogen; Lyso-PE (Plasmalogen); sn-Glycero-3-phosphoethanolamine Lysoplasmalogen; Brain Lysophospholipid
EINECS	Contact for details

Quality Control

Every batch of L-α-Lysophosphatidylethanolamine Plasmalogen (Brain, Porcine) is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency suitable for sensitive research applications. Our quality system emphasizes traceability and documentation. Comprehensive Certificates of Analysis (COA) detailing purity (by HPLC), fatty acyl chain profile, and absence of critical impurities are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). The product is easily oxidized and moisture-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR & NMR)	Conforms to structure
Assay (HPLC)	≥ 95% (Total Plasmalogen Content)
Purity (HPLC, Area %)	≥ 98%
Solubility	Soluble in chloroform, methanol, ethanol; forms micelles in aqueous buffer
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines
Microbial Limits	< 100 CFU/g (Total Aerobic Microbial Count)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.