Description

(2S)-2-Methylpiperazine Dihydrochloride is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for creating molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise chirality control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Agrochemical Development: Employed in the synthesis of advanced, stereospecific pesticides and herbicides.
• Chemical Research: Serves as a valuable reference standard and starting material in academic and industrial research exploring piperazine chemistry.
• Peptidomimetics: Incorporated into the design of peptide-like molecules to modulate biological pathways with improved metabolic stability.

Basic Information

Product Name	(2S)-2-Methylpiperazine Dihydrochloride
CAS No.	475640-80-3
Molecular Formula	C5H14Cl2N2
Molecular Weight	173.08 g/mol
Synonyms	(S)-2-Methylpiperazine Dihydrochloride; (2S)-2-Methylpiperazine Hydrochloride; (S)-2-Methylpiperazine Dihydrochloride; L-2-Methylpiperazine Dihydrochloride; (S)-2-Methylpiperazine-1,4-diium Chloride; (S)-2-Methylpiperazine-1,4-diium Dichloride; (S)-2-Methylpiperazinium Chloride; (2S)-2-Methylpiperazine-1,4-diium Dichloride
EINECS	Contact for details

Quality Control

Our (2S)-2-Methylpiperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.