Description

(S)-1-Boc-3-Benzylpiperazine is a high-purity chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. Its value lies in providing a protected, stereochemically defined scaffold essential for constructing complex molecules with high biological specificity. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• API Development: Used in constructing the core pharmacophore of potential therapeutic agents in preclinical and clinical research.
• Asymmetric Synthesis: Serves as a versatile starting material for creating libraries of enantiomerically pure compounds for screening.
• Peptidomimetics: Incorporated into the design of peptide-like molecules to enhance metabolic stability and bioavailability.
• Ligand & Catalyst Preparation: Utilized in the preparation of chiral ligands for asymmetric catalysis.
• Chemical Biology Research: Employed as a molecular probe or tag in studying biological pathways and protein interactions.

Basic Information

Product Name	(S)-1-Boc-3-Benzylpiperazine
CAS No.	475272-55-0
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-3-benzylpiperazine; (S)-3-Benzyl-1-Boc-piperazine; tert-Butyl (S)-3-benzylpiperazine-1-carboxylate; (S)-1-Boc-3-benzylpiperazine; (S)-N-Boc-3-benzylpiperazine; (S)-3-Benzylpiperazine-1-carboxylic acid tert-butyl ester; (S)-1-(tert-Butyloxycarbonyl)-3-benzylpiperazine; (S)-Boc-3-benzylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-3-Benzylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.