Description

(S)-1-n-Boc-3-Isopropylpiperazine is a high-purity, chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical, protected building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex molecules requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Peptidomimetic Synthesis: Used to introduce the (S)-3-isopropylpiperazine moiety into peptide backbones to modulate biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways.
• Custom Synthesis Building Block: Provides a versatile, protected amine handle for multi-step synthetic routes in contract research and manufacturing (CRO/CMO).

Basic Information

Product Name	(S)-1-n-Boc-3-Isopropylpiperazine
CAS No.	475272-54-9
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(S)-1-Boc-3-isopropylpiperazine; (S)-3-Isopropyl-1-(tert-butoxycarbonyl)piperazine; tert-Butyl (S)-3-(propan-2-yl)piperazine-1-carboxylate; (S)-1-(tert-Butoxycarbonyl)-3-isopropylpiperazine; (S)-N-Boc-3-isopropylpiperazine; (S)-3-Isopropyl-1-Boc-piperazine; (S)-1-N-Boc-3-isopropylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-n-Boc-3-Isopropylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.