Description

( 2-{4-[n-(5,6-Diphenylpyrazin-2-Yl)-n-Isopropylamino]Butyloxy}Acetic Acid tert-Butylester ) is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for targeted synthesis. This compound matters as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncology.
• Research Chemical: Used in academic and industrial research to study structure-activity relationships (SAR) and develop new chemical entities with pyrazine and diphenyl moieties.
• API Development: Employed in the development and scale-up processes for new Active Pharmaceutical Ingredients requiring a tert-butyl ester-protected acetic acid linker attached to a functionalized pyrazine core.
• Fine Chemical Synthesis: A valuable reagent for constructing complex molecules in custom synthesis and process chemistry for the fine chemical and agrochemical industries.
• Bioconjugation & Prodrug Synthesis: The tert-butyl ester group offers a protective strategy, making this compound useful in designing prodrugs or bioconjugation linkers that can be cleaved under specific conditions.

Basic Information

Product Name	( 2-{4-[n-(5,6-Diphenylpyrazin-2-Yl)-n-Isopropylamino]Butyloxy}Acetic Acid tert-Butylester )
CAS No.	475084-96-9
Molecular Formula	C31H37N3O3
Molecular Weight	499.65 g/mol
Synonyms	2-[4-[N-(5,6-Diphenylpyrazin-2-yl)-N-isopropylamino]butoxy]acetic acid tert-butyl ester; tert-Butyl 2-[4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butoxy]acetate; 2-{4-[N-(5,6-Diphenylpyrazin-2-yl)-N-isopropylamino]butoxy}acetic acid 1,1-dimethylethyl ester; 475084-96-9; UNII-9J8K4A8U5Q; 9J8K4A8U5Q; SCHEMBL218064; AKOS009158932; AS-76311.
EINECS	Contact for details

Quality Control

Our ( 2-{4-[n-(5,6-Diphenylpyrazin-2-Yl)-n-Isopropylamino]Butyloxy}Acetic Acid tert-Butylester ) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with specifications that can meet GMP-grade requirements for advanced intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.