Description

18:1 Epc (Cl Salt) is a high-purity, synthetic phospholipid derivative, specifically a chloride salt form of a phosphatidylcholine analog. This compound is critical for advanced research and development in life sciences, offering a defined and consistent chemical structure essential for reproducible results. It serves as a fundamental building block for formulation scientists and researchers in the pharmaceutical, biotechnology, and advanced material sectors, particularly in the development of lipid-based delivery systems such as liposomes and lipid nanoparticles (LNPs).

Application

• Lipid Nanoparticle (LNP) Formulation: A key synthetic lipid component for constructing stable, non-viral delivery vehicles for mRNA, siRNA, and other nucleic acid therapeutics.
• Liposome & Vesicle Preparation: Used in the manufacture of model membranes and drug delivery carriers for encapsulating hydrophilic and hydrophobic active ingredients.
• Biomimetic Membrane Research: Employed in biophysical studies to create synthetic cell membranes with controlled composition for permeability and interaction studies.
• Pharmaceutical Excipient: Acts as a functional excipient in advanced parenteral formulations to enhance solubility, stability, and bioavailability of poorly soluble drugs.
• Diagnostic Reagent Development: Utilized in the formulation of contrast agents or as a component in diagnostic assay kits requiring specific membrane interactions.
• Cell Culture & Transfection: Aids in the development of specialized media supplements and transfection reagents for in vitro studies.

Basic Information

Product Name	18:1 Epc (Cl Salt)
CAS No.	474945-24-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,2-dioleoyl-sn-glycero-3-ethylphosphocholine chloride; EPC (Cl Salt); Ethylphosphatidylcholine chloride (18:1); DO-EPC chloride; 1,2-Dioleoyl-3-ethylphosphocholine chloride; Ethyl-PC (18:1/18:1) chloride salt; Synthetic phospholipid chloride salt
EINECS	Contact for details

Quality Control

Every batch of 18:1 Epc (Cl Salt) is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include data from advanced techniques such as NMR, HPLC, and mass spectrometry. Our quality commitment supports applications requiring GMP-grade materials for preclinical and clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.