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1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-Lactosyl (Ammonium Salt) CAS NO 474943-47-0


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CAS No.:474943-47-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-Lactosyl (Ammonium Salt) is a synthetic, high-purity phospholipid conjugate designed for advanced research and formulation applications. This specialized compound is critical for constructing biomimetic lipid membranes and targeted delivery systems due to its unique lactosyl head group. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and diagnostic sectors for creating liposomal drug carriers, studying membrane interactions, and developing novel cell-targeting platforms.

Application

  • Liposomal Drug Delivery Systems: A key functional component for formulating ligand-targeted liposomes, enhancing drug delivery to specific cell types.
  • Biomimetic Membrane Research: Used in the construction of model membranes (e.g., vesicles, supported lipid bilayers) to study carbohydrate-mediated cell recognition and signaling processes.
  • Diagnostic Reagent Formulation: Serves as a surface ligand in diagnostic assays and imaging agents for targeted detection of lectin-expressing cells.
  • Gene Delivery Vectors: Incorporated into non-viral transfection complexes to improve cellular uptake and targeting efficiency.
  • Cell Culture & Biochemistry: Employed in studies of glycolipid metabolism, membrane fusion, and as a tool for investigating carbohydrate-protein interactions.
  • Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a bioactive ingredient for advanced skin delivery systems.

Basic Information

Product Name 1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-Lactosyl (Ammonium Salt)
CAS No. 474943-47-0
Molecular Formula C71H130N2O19P
Molecular Weight 1363.79 g/mol
Synonyms Lactosyl PE; DOPE-Lactose; 18:1 Lactosyl PE; Lactosyl-DOPE; N-(Lactosyl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine ammonium salt; Lactosylphosphatidylethanolamine; Glycolipid PE conjugate; Lactose-PE
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Quality Control

Every batch of our 1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-Lactosyl (Ammonium Salt) is produced under strict quality management systems and undergoes comprehensive analytical characterization. We ensure high purity and batch-to-batch consistency through advanced techniques like HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and critical specifications are provided to guarantee compliance with your research and cGMP-grade formulation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (e.g., argon or nitrogen). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Complies
Identification (NMR) Complies
Assay (HPLC) ≥ 95%
Solubility Soluble in chloroform, methanol, DMSO; forms micelles in water
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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