Description

18:1 Semi Lbpa (S,R) is a high-purity, stereochemically defined lysophospholipid derivative, specifically a semi-synthetic lysophosphatidic acid (LPA) analog. This compound is a critical research-grade biochemical tool for investigating lipid signaling pathways, particularly those mediated by LPA receptors (LPARs). It is essential for scientists and product developers in the pharmaceutical, biotechnology, and advanced life science research sectors who require precise molecular probes for target validation, assay development, and drug discovery.

Application

• Biochemical Research: As a potent and selective agonist/antagonist (depending on stereochemistry) for lysophosphatidic acid (LPA) receptor studies in cell signaling and pharmacology.
• Drug Discovery & Development: A key intermediate or reference standard in the synthesis and screening of novel therapeutics targeting LPARs for conditions like fibrosis, cancer, and neuropathic pain.
• Cell Culture & Physiology: Used to stimulate specific cellular responses such as proliferation, migration, and differentiation in various cell-based assay systems.
• Lipidomics & Analytical Standards: Serves as a high-purity certified reference material (CRM) for mass spectrometry, chromatography, and quantitative lipid analysis.
• Formulation Research: Investigated in the development of advanced lipid-based drug delivery systems, including liposomes and nanoparticles.

Basic Information

Product Name	18:1 Semi Lbpa (S,R)
CAS No.	474943-36-7
Molecular Formula	C21H41NO7P
Molecular Weight	450.52 g/mol
Synonyms	1-Oleoyl-2-hydroxy-sn-glycero-3-phosphate; (S,R)-1-Oleoyl-2-hydroxy-sn-glycerol-3-phosphate; 18:1 LPA (S,R); Lysophosphatidic Acid (18:1, semi, S,R isomer); LPA (18:1); 1-(9Z-Octadecenoyl)-2-hydroxy-sn-glycero-3-phosphoric acid; Oleoyl Lysophosphatidic Acid; Research Grade LPA Analog
EINECS	Contact for details

Quality Control

Every batch of 18:1 Semi Lbpa (S,R) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and stereochemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results from NMR, HPLC, and MS analysis.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen), as the compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Enantiomeric Excess (Chiral HPLC)	≥ 98%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.