Description

D-Erythro-Sphingosine-1-Phosphate (C17 Base) is a high-purity, bioactive sphingolipid metabolite essential for cellular signaling research and development. This compound serves as a critical reference standard and key intermediate in the synthesis of more complex signaling molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, metabolic pathway studies, and the development of novel therapeutics targeting sphingolipid-related diseases.

Application

• Biomedical Research: As a critical reference standard and reagent for studying sphingosine-1-phosphate (S1P) receptor signaling pathways, cell proliferation, migration, and apoptosis.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel drug candidates and molecular probes targeting S1P receptors for autoimmune diseases, cancer, and inflammatory disorders.
• Cell Culture & Biochemistry: Used in cell-based assays to investigate the role of S1P in angiogenesis, vascular development, and immune cell regulation.
• Metabolomics & Lipidomics: An essential analytical standard for the accurate quantification and profiling of sphingolipid metabolites in biological samples using LC-MS/MS and other advanced techniques.
• Enzyme Substrate: Employed as a substrate for sphingosine kinase (SphK) activity assays in both academic and industrial research settings.

Basic Information

Product Name	D-Erythro-Sphingosine-1-Phosphate (C17 Base)
CAS No.	474923-27-8
Molecular Formula	C17H38NO5P
Molecular Weight	367.46 g/mol
Synonyms	Sphingosine-1-phosphate (C17); D-erythro-S1P; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-Phosphate; S1P (C17 Base); D-erythro-Sphingosine 1-Phosphate; Sphing-4-enine-1-phosphate; (2S,3R,4E)-2-Azaniumyl-4-octadecene-1,3-diol 1-dihydrogen phosphate; Lipid Mediator S1P
EINECS	Contact for details

Quality Control

Our D-Erythro-Sphingosine-1-Phosphate (C17 Base) is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous analytical standards, with testing typically performed via HPLC, NMR, and MS to confirm structure and potency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to minimize condensation and hydrolysis. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.