Description

n-Lauroyl-D-Erythro-Sphingosylphosphorylcholine is a synthetic, high-purity sphingolipid derivative, specifically a lauroylated sphingosylphosphorylcholine. This compound serves as a critical biochemical tool and a key intermediate in advanced lipidomics research and the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of cell signaling, membrane biology, and metabolic pathways. Its defined structure provides a reliable standard for analytical work and the synthesis of more complex bioactive molecules.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in mass spectrometry (MS) and liquid chromatography (LC) for the quantification and identification of sphingolipids in biological samples.
• Cell Signaling Studies: Employed in vitro to investigate the role of specific sphingolipid metabolites in apoptosis, proliferation, and other cellular processes.
• Pharmaceutical Intermediate: Acts as a key synthetic building block for the development of novel drug candidates targeting sphingolipid-related diseases.
• Lipidomics & Metabolomics: Essential for creating calibration curves and spiking samples in quantitative lipidomic profiling to understand metabolic disorders.
• Membrane Biophysics: Used in model membrane systems (e.g., liposomes) to study the effects of specific lipid structures on membrane fluidity and protein-lipid interactions.
• Enzyme Substrate/Inhibitor Studies: Serves as a defined substrate for enzymes like sphingomyelinases or ceramidases in kinetic and mechanistic studies.

Basic Information

Item	Detail
Product Name	n-Lauroyl-D-Erythro-Sphingosylphosphorylcholine
CAS No.	474923-21-2
Molecular Formula	C40H81N2O7P
Molecular Weight	733.06 g/mol
Synonyms	Lauroyl Sphingosylphosphorylcholine; N-Lauroyl-D-erythro-sphingosylphosphorylcholine; Sphingosylphosphorylcholine Lauroyl Derivative; Lauroyl-SPC; C12:0 Sphingosylphosphorylcholine; N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]lauroylphosphorylcholine; Lyso-N-lauroyl-sphingomyelin; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-Lauroyl-D-Erythro-Sphingosylphosphorylcholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS/NMR for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every lot. We support research and development with materials suitable for use as analytical standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.