Description

Piperazine-1-Carboxylic Acid Amide Hcl is a high-purity, functionalized piperazine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, where the piperazine moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and other bioactive molecules that mimic natural peptides.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	Piperazine-1-Carboxylic Acid Amide Hcl
CAS No.	474711-89-2
Molecular Formula	C5H12N3O•HCl
Molecular Weight	181.63 g/mol
Synonyms	1-Piperazinecarboxamide Hydrochloride; Piperazine-1-carboxamide Hydrochloride; Piperazinecarboxamide Monohydrochloride; 1-Carbamoylpiperazine Hydrochloride; Piperazine-1-Carboxylic Acid Amide Hydrochloride; UNII-6J3C5K6K1P; Amide, Piperazine-1-carboxylic Acid, Hydrochloride
EINECS	Contact for details

Quality Control

Our Piperazine-1-Carboxylic Acid Amide Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring material traceability and compliance with cGMP, ISO, and other relevant regulatory guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.