Description

tert-Butyl 4-(2-Amino-4-Bromophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with both amino and bromo functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers seeking reliable, high-quality building blocks for drug discovery and process development.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of novel pharmaceutical compounds, especially those targeting neurological disorders.
• Drug Discovery & Medicinal Chemistry: Used in research and development for creating and optimizing new chemical entities (NCEs) due to its versatile piperazine scaffold.
• Precursor for Biologically Active Molecules: The reactive amino and bromo groups allow for further functionalization, making it a precursor for ligands, inhibitors, and receptor modulators.
• Fine Chemical Manufacturing: Employed in multi-step organic synthesis for producing complex, high-value specialty chemicals.

Basic Information

Product Name	tert-Butyl 4-(2-Amino-4-Bromophenyl)Piperazine-1-Carboxylate
CAS No.	474329-58-3
Molecular Formula	C15H22BrN3O2
Molecular Weight	356.26 g/mol
Synonyms	1-Boc-4-(2-Amino-4-bromophenyl)piperazine; 4-(2-Amino-4-bromophenyl)-1-(tert-butoxycarbonyl)piperazine; tert-Butyl 4-(2-amino-4-bromophenyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(2-amino-4-bromophenyl)-, 1,1-dimethylethyl ester; 474329-58-3; Boc-4-(2-Amino-4-bromophenyl)piperazine; N-Boc-4-(2-Amino-4-bromophenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Amino-4-Bromophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.