Description

1H-Indazole-3-Acetyl Chloride, α-Oxo- (9Ci) is a high-purity, reactive chemical building block belonging to the indazole class of heterocyclic compounds. This specialized intermediate is critical for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Biology Research: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Potential precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	1H-Indazole-3-Acetyl Chloride, α-Oxo- (9Ci)
CAS No.	474011-82-0
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	1H-Indazole-3-carbonyl chloride, 1-oxo-; 1H-Indazole-3-glyoxyloyl chloride; 3-(Chlorooxoacetyl)-1H-indazole; α-Oxo-1H-indazole-3-acetyl chloride; 1H-Indazole-3-carboxylic acid, oxo-, chloride; 474011-82-0; 3-Glyoxyloyl chloride-1H-indazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole-3-Acetyl Chloride, α-Oxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.