Description

(R)-1-Benzoyl-3-Methylpiperazine Hydrochloride CAS NO 474010-60-1 is a high-purity chiral piperazine derivative, specifically the (R)-enantiomer, supplied as a hydrochloride salt. This compound serves as a critical chiral building block and intermediate in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on central nervous system (CNS) agents, receptor modulators, and other fine chemical syntheses.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in neurological and psychiatric drug discovery.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective chemical reactions to introduce the (R)-configured methylpiperazine moiety.
• Medicinal Chemistry Research: A valuable scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Potential intermediate in the synthesis of advanced chiral pesticides and herbicides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations requiring high-quality, well-defined chiral intermediates for custom synthesis projects.
• Academic Research: Used in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-1-Benzoyl-3-Methylpiperazine Hydrochloride
CAS No.	474010-60-1
Molecular Formula	C12H17ClN2O
Molecular Weight	240.73 g/mol
Synonyms	(R)-1-Benzoyl-3-methylpiperazine HCl; (R)-3-Methyl-1-(phenylcarbonyl)piperazine hydrochloride; (R)-N-Benzoyl-3-methylpiperazine hydrochloride; (R)-1-(Benzoyl)-3-methylpiperazine hydrochloride; (R)-Benzoyl-3-methylpiperazine HCl; (R)-1-Benzoyl-3-methylpiperazine monohydrochloride; (R)-Bz-3-Me-piperazine•HCl
EINECS	Contact for details

Quality Control

Our (R)-1-Benzoyl-3-Methylpiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.