Description

Methyl 4-(3-Amino-2-Hydroxybenzoyl)Piperazine-1-Carboxylate is a high-purity, functionalized piperazine derivative serving as a critical pharmaceutical intermediate and research chemical. This compound is valued for its unique molecular scaffold, which combines an amino-hydroxybenzoyl moiety with a piperazine core, making it a versatile building block for drug discovery and development. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for creating novel active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a precursor for more complex heterocyclic compounds and functionalized piperazine derivatives.
• API Development: Integral in the development and scale-up processes for new active pharmaceutical ingredients.
• Bioconjugation & Probe Synthesis: Potential use in creating biochemical probes and labeled compounds for diagnostic research.

Basic Information

Product Name	Methyl 4-(3-Amino-2-Hydroxybenzoyl)Piperazine-1-Carboxylate
CAS No.	473734-26-8
Molecular Formula	C13H17N3O4
Molecular Weight	279.29 g/mol
Synonyms	Methyl 4-(3-amino-2-hydroxybenzoyl)piperazine-1-carboxylate; 1-Carbomethoxy-4-(3-amino-2-hydroxybenzoyl)piperazine; 4-(3-Amino-2-hydroxybenzoyl)piperazine-1-carboxylic acid methyl ester; Piperazine-1-carboxylic acid, 4-(3-amino-2-hydroxybenzoyl)-, methyl ester; Methyl N-carboxy-4-(3-amino-2-salicyloyl)piperazine
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(3-Amino-2-Hydroxybenzoyl)Piperazine-1-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. The material is manufactured under a quality management system and undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications such as assay, related substances, and residual solvents to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.