Description

(3-Amino-2-Hydroxyphenyl)(4-(Methylsulfonyl)Piperazin-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure combining an aminohydroxyphenyl moiety with a methylsulfonyl piperazine group. This compound is of significant value in modern medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex, targeted molecules for potential drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable functional groups.
• Biochemical Tool Compound: Acts as a precursor or reference standard in the development of enzyme inhibitors or receptor modulators for biochemical assays.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex heterocyclic compounds with potential biological activity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for preclinical and clinical-stage molecules.

Basic Information

Product Name	(3-Amino-2-Hydroxyphenyl)(4-(Methylsulfonyl)Piperazin-1-Yl)Methanone
CAS No.	473734-22-4
Molecular Formula	C12H15N3O4S
Molecular Weight	297.33 g/mol
Synonyms	1-(3-Amino-2-hydroxybenzoyl)-4-(methylsulfonyl)piperazine; 4-(Methylsulfonyl)-1-[(3-amino-2-hydroxyphenyl)carbonyl]piperazine; Methanone, (3-amino-2-hydroxyphenyl)[4-(methylsulfonyl)-1-piperazinyl]-; 4-Methanesulfonyl-piperazine-1-carboxylic acid (3-amino-2-hydroxy-phenyl)-amide; (3-Amino-2-hydroxy-benzoyl)-[4-(methane-sulfonyl)-piperazin-1-yl]-methanone
EINECS	Contact for details

Quality Control

Our production of (3-Amino-2-Hydroxyphenyl)(4-(Methylsulfonyl)Piperazin-1-Yl)Methanone adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Our quality commitment supports reliable and reproducible results in your downstream synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.