Description

1-Pyridin-3-Yl-Piperazine Dihydrochloride is a high-purity, versatile heterocyclic building block and intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical companies, and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for designing and optimizing new chemical entities (NCEs) in drug discovery programs, especially for kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of specialty chemicals for various industrial applications.

Basic Information

Product Name	1-Pyridin-3-Yl-Piperazine Dihydrochloride
CAS No.	470441-67-9
Molecular Formula	C9H14N4·2HCl
Molecular Weight	263.16 g/mol
Synonyms	3-(1-Piperazinyl)pyridine Dihydrochloride; 1-(Pyridin-3-yl)piperazine Dihydrochloride; 3-Piperazin-1-ylpyridine Dihydrochloride; 1-(3-Pyridyl)piperazine Dihydrochloride; N-(Pyridin-3-yl)piperazine Dihydrochloride; 3-(Piperazin-1-yl)pyridine Dihydrochloride; 1-Pyridin-3-ylpiperazine Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Pyridin-3-Yl-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.