Description

1-Piperazineethanethiol,4-(2-Aminoethyl)-(9Ci) is a specialized organic compound featuring a piperazine core functionalized with both thiol and aminoethyl groups. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by researchers and manufacturers in the life sciences sector for creating novel drug candidates and biochemical probes. The compound is supplied with a high level of purity to ensure consistent performance in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and receptor-based pathways.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates, leveraging its thiol group for selective coupling.
• Ligand Synthesis: Serves as a precursor for creating chelating agents and ligands used in catalysis and metal ion binding studies.
• Polymer Modification: Employed to introduce functional thiol and amine groups into polymer backbones for advanced material science applications.
• Peptidomimetic Research: Integral in the design and synthesis of peptidomimetics and other bioactive compounds that mimic natural peptides.
• Chemical Biology Probes: Utilized to create probes for studying enzyme activity, protein interactions, and cellular processes.

Basic Information

Product Name	1-Piperazineethanethiol,4-(2-Aminoethyl)-(9Ci)
CAS No.	464894-56-2
Molecular Formula	C8H19N3S
Molecular Weight	189.32 g/mol
Synonyms	4-(2-Aminoethyl)piperazine-1-ethanethiol; 2-[4-(2-Aminoethyl)piperazin-1-yl]ethanethiol; 1-Piperazineethanethiol, 4-(2-aminoethyl)-; N-(2-Aminoethyl)-N'-(2-mercaptoethyl)piperazine; 2-(4-(2-Aminoethyl)piperazin-1-yl)ethan-1-thiol; AE-Pip-SH (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Piperazineethanethiol,4-(2-Aminoethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.